Pros
Generous compensation and benefits, at least as of now (although benefits and compensation are being curtailed). Some talented co-workers and top notch scientists but most of the top talent is leaving because of recent changes.
Cons
No clear direction from Sr. Management. A chaotic environment where urgent projects are cancelled without notice, sites are closed and colleagues relocated yearly, years of work are discarded and each wave of re-organization lowers morale further. Positions are often created, filled and then eliminated within a 6-10 month time frame. Pfizer has a long history of hiring people into sites that close within a week of their start date. The leadership has proven time and again to be completely untrustworthy. Whatever they say, believe the opposite. Beware working for this company.